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Epigenetics-focused Epizyme gains $90M upfront in deal with Celgene on targeted cancer therapies

This article was originally published in Scrip

Executive Summary

Epizyme, a US private firm founded in 2007 to focus on discovering new drugs based on epigenetic mechanisms, has formed a strategic partnership with oncology company Celgene that leverages the strengths of both companies. By working on joint programmes on a global basis, two firms hope to bring to market personalised therapies for patients with genetically defined cancers by inhibiting histone methytransferases (HMTs), an important epigenetic class.

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