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Vertex Pharmaceuticals said on 18 March the FDA had expanded the use of the company's cystic fibrosis drug Kalydeco (ivacaftor) in children 2-5 years who have one of 10 mutations in the CF transmembrane conductance regulator (CFTR) gene: G551D, G1244E, G1349D, G178R, G551S, S1251N, S1255P, S549N, S549R and R117H.
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