Chinese, Canadian Researchers ID Anti-Bird Flu Compound
This article was originally published in PharmAsia News
Executive Summary
Hong Kong and Canadian scientists working on a genome technology report found a compound that inhibits the H5N1 bird flu virus. The team said it tested 20 compounds and found one it labeled "compound-1" that inhibits neuraminidase involved in viral replication. The compound was found to operate at a level similar to oseltamivir, the active ingredient in Roche's Tamiflu, known to be losing its effectiveness against the virus. The identified compound was able to bind to the neuraminidase of the virus and, according to the researchers, might overcome the drug resistance. (Click here for more