SmartCells Inc.
This article was originally published in Start Up
Executive Summary
SmartCells' SmartInsulin is a once-daily subcutaneous injectable formulation of insulin for the treatment of type 1 and type 2 diabetes. SmartInsulin comprises insulin molecules conjugated to a biocompatible and biodegradable polymer, which binds to a multivalent glucose-binding molecule. Once injected, it self-assembles to form an insoluble matrix. Insulin is released from the system only when the therapeutic is unbound by the presence of a specific glucose concentration.