FDA OK's Lilly's Taltz; Rival To Novartis' Cosentyx
This article was originally published in Scrip
In giving its blessing to Eli Lilly & Co. on March 22 to market Taltz (ixekizumab) as a treatment for adults with moderate-to-severe plaque psoriasis, the FDA created a new rivalry for Novartis AG's medicine Cosentyx (secukinumab).
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VP Rebecca Morison said the ankylosing spondylitis indication adds more evidence of Taltz's benefits. She noted Lilly believes there should be fewer steps before AS patients access IL-17 inhibitors.
Although its focus may be shifting somewhat towards other indications, the Swiss major has reported study read-outs that demonstrate the long-term efficacy of its IL-17A inhibitor blockbuster in nail and palmoplantar psoriasis.
Next up for Cosentyx is psoriatic arthritis and ankylosing spondylitis. Novartis presented impressive long-term efficacy data at ACR in PsA and AS. Incoming CEO and Chief Medical Officer Vas Narasimhan said the company sees a blockbuster opportunity and is exploring the anti-TNF naïve market in AS.