Scrip is part of Pharma Intelligence UK Limited

This site is operated by Pharma Intelligence UK Limited, a company registered in England and Wales with company number 13787459 whose registered office is 5 Howick Place, London SW1P 1WG. The Pharma Intelligence group is owned by Caerus Topco S.à r.l. and all copyright resides with the group.

This copy is for your personal, non-commercial use. For high-quality copies or electronic reprints for distribution to colleagues or customers, please call +44 (0) 20 3377 3183

Printed By


Discounts Sway NICE As Novartis Outlines Concerns Over New Cancer Drugs Fund

Executive Summary

NICE – the HTA body for England and Wales – has recommended that Novartis's Zykadia (ceritinib) be available on the NHS, but only at a discount. Novartis tells Scrip that with the imminent arrival of the UK's new Cancer Drugs Fund (CDF), there are concerns that access to new cancer drugs will become even more difficult.

You may also be interested in...

NICE Clears Amgen’s Imlygic At Second Attempt, Combo Results Keenly Awaited

A completely new form of therapy, the use of viruses to kill cancer cells, is now recommended by NICE for use in melanoma patients in England in final draft guidance, although its future therapeutic and commercial success may depend on positive findings from ongoing combination studies with checkpoint inhibitors and other immunotherapies.

PCSK9s: Discount Prompts NICE Turnaround on Sanofi's Praluent

HTA body NICE has Okayed PCSK9 inhibitors Repatha and Praluent for adults with primary hypercholesterolaemia or mixed dyslipidaemia for use on the National Health Service IN England and Wales. However, restrictions on prescribing will likely limit sales.

IQWiG: Tafinlar/Mekinist Benefit 'Considerable' In Men With Melanoma, But Still Better In Women

Germany's HTA body IQWiG has declared that there is "an indication of a considerable added benefit for men" of the combination of Novartis' Tafinlar and Mekinist (dabrafenib and trametinib).

Related Content


Latest Headlines
See All



Ask The Analyst

Ask the Analyst is free for subscribers.  Submit your question and one of our analysts will be in touch.

Thank you for submitting your question. We will respond to you within 2 business days. my@email.address.

All fields are required.

Please make sure all fields are completed.

Please make sure you have filled out all fields

Please make sure you have filled out all fields

Please enter a valid e-mail address

Please enter a valid Phone Number

Ask your question to our analysts