Protein Production Start-Ups
This article was originally published in Start Up
Executive Summary
Should a disruptive protein production technology emerge, the current interest in developing large-molecule therapeutics assures there would be many takers.
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Pfizer Opts for Access Over Exclusivity in Antibodies
For its biggest antibody deal to date, Pfizer choose Medarex, which insists on non-exclusive agreements, leaving the biotech free to work with other partners on any given target. In doing so, Pfizer reckoned that the potential for competition with respect to a particular target was outweighed by the greater access to targets which Medarex's deal model provides.
Pfizer Opts for Access Over Exclusivity in Antibodies
For its biggest antibody deal to date, Pfizer choose Medarex, which insists on non-exclusive agreements, leaving the biotech free to work with other partners on any given target. In doing so, Pfizer reckoned that the potential for competition with respect to a particular target was outweighed by the greater access to targets which Medarex's deal model provides.
Psyche Pharmaceuticals Inc.
Psyche Pharmaceuticals aims to commercialize a technique for the chemical synthesis of proteins, which theoretically allows for the insertion of unnatural amino acids and thus, custom design of therapeutic proteins. The new method combines aspects of solution-based and solid-phase approaches to peptide synthesis, and also harnesses mass spectroscopy. For now, the start-up aims to sell peptides, particularly chemokines, into the research market.