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Moving Beyond Accutane and Botox

This article was originally published in Start Up

Executive Summary

Ever hungry for new investment opportunities, VCs are now backing start-ups developing novel dermatology products for both medical and cosmetic conditions. These aren't your typical "derm" companies. Not content to invent new delivery vectors for existing medicines or reformulate them into more patient friendly creams, these fledgling companies are trying to develop new chemical entities based on novel skin biology.

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A $12-billion market and growing, the field of aesthetic medicine has exploded with new treatments and techniques for improving and restoring the quality, health and appearance of aging skin. Techniques such as tissue tightening, skin resurfacing, cellulite treatments, dermal augmentation, and fat removal are just some of the new advancements in aesthetic medicine that were highlighted at the 2007 American Academy of Dermatology meeting.

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Much of the innovation in cosmetic dermatology has come from the multibillion-dollar, largely unregulated cosmeceuticals industry. But Kythera Biopharmaceuticals aims to bring true, rigorous clinical science to the field, with prescription drugs that modulate novel biological pathways in aesthetic and restorative indications.

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