AZ’s ZS-9 Targets Hyperkalemia Sector As It Nears EU Market
A potential near-blockbuster drug, AstraZeneca’s Lokelma (ZS-9), has received a positive opinion from Europe’s CHMP and, if approved, will soon have to justify best-in-class plaudits and a hefty acquisition price.
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Rival Vifor Pharma has predicted blockbuster status for Veltassa and AstraZeneca expects the same for its just-approved oral potassium-removing agent, hoping that Lokelma's faster onset of action will help it win the fight for market share in hyperkalemia.
The treatment of hyperkalemia in Europe in patients with chronic kidney disease or chronic heart failure looks set to become more vibrant, with AstraZeneca's Lokelma likely to join Vifor Pharma's Veltassa in the marketplace.
A Swiss IPO for retail pharmacy and distributor spin-off Galenica Santé has allowed the remaining specialty firm Vifor Pharma to become a pure play pharma with a potential blockbuster potassium binder Veltassa and interests in renal disease, iron replacement and cardio-renal disorders.