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Poseida Therapeutics, Inc.

http://poseida.com/

Latest From Poseida Therapeutics, Inc.

Risk/Benefit Of CAR-T For Autoimmune Diseases May Shift With FDA Investigation

CAR-T therapy-associated T-cell malignancies that the US FDA is investigating could make the treatments less attractive in autoimmune diseases than in oncology, but patients in both settings already accept some cancer risk with other available medicines.

Drug Safety ImmunoOncology

CAR-T Safety Probe Causes Alarm, But Is Unlikely To Upend Therapies

Hopes are that the impact of the US FDA’s investigation into a small number of T-cell malignancies associated with CAR-T therapies will be small since the benefit/risk profile still looks sound.

Drug Safety Cancer

Finance Watch: Sage Warns Of Job Cuts, Joins Peers Making Cash Last After Setbacks

Public Company Edition: Sage will reveal cost reductions later in the third quarter after the US FDA approved zuranolone for the smaller of two depression indications. Also, Karyopharm revealed a 20% workforce reduction, Harmony accessed up to $185m in debt and Astellas invested $50m in Poseida.

Financing Restructuring

Myeloma Market Snapshot: New Drug Classes On The Way, But Cost Could Be A Problem

More BCMA-directed therapies are in development, as well as ones targeting GPRC5D and FcRH5, along with CELMoDs. The question is how to bring those into therapy and pay for them.

Market Snapshot ImmunoOncology
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    • Transposagen Biopharmaceuticals, Inc.
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